Yes, the lines of the hand change throughout life. The main lines (heart, head, life) evolve slowly over several years, while secondary lines can appear or fade in a few months. Changes often reflect notable events, intense emotions, and big decisions crossed.
Lines that move slowly
The major lines, heart, head, life, are formed in utero and stay globally stable throughout life.
They deepen, lengthen, sometimes fragment, but their general tracing stays recognizable from one decade to the next.
Lines that move fast
Secondary lines, fate line, sun line, marriage lines, small branches, can appear or disappear in a few months.
An intense stress period carves new marks. A calming phase can fade a broken line.
What triggers changes
Big emotional breaks leave crossings on the heart line.
Career changes often redraw the fate line.
Physical shocks or motherhoods can thicken the life line or bring out a parallel support line.
How to see the change yourself
Take a photo of both palms once a year, at the same time and under the same light.
Compare every two or three years: you'll see differences your eyes don't catch daily.